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Genocea herpes vaccine wins industry award

April 12, 2017

Genocea Biosciences, Inc. (NASDAQ:GNCA), a biopharmaceutical company developing T cell-directed vaccines and immunotherapies, today announced that it has been awarded the World Vaccine Congress 2017 Industry Excellence award for best therapeutic vaccine for GEN-003, an immunotherapy to treat genital herpes, which is expected to be Phase 3 ready by the end of 2017.

In addition, the company is giving two oral presentations and participating on a panel at the congress, which is taking place from April 10-12 in Washington DC. The two presentations highlight the success to date of Genocea’s ATLAS™ technology, a proprietary T cell immune response screening platform designed to identify clinically relevant T cell antigens. Using ATLAS, Genocea is building a pipeline of candidates that includes GEN-003 and GEN-009, a neoantigen cancer vaccine, for which the company expects to file an Investigational New Drug (IND) application by the end of 2017.

  • “Developing an HSV vaccine to control clinical recurrences and viral shedding”
    Tuesday, April 11 at 12:10 pm ET
    Thomas Heineman, M.D., Ph.D., Genocea’s Vice President of Clinical Development
    In his presentation, Dr. Heineman will provide a comprehensive overview of GEN-003: its rational design and positive clinical results to date.
  • “Comprehensive profiling of T cell responses to putative neoantigens reveals smarter targets for cancer immunotherapy”
    Wednesday, April 12 at 12:00 pm ET
    Jessica Baker Flechtner, Ph.D., Genocea’s Chief Scientific Officer
    In her presentation, Dr. Flechtner will provide an overview of the company’s ATLAS technology: its advantages over predictive methods of antigen identification, and how Genocea is using ATLAS to develop neoantigen cancer vaccines and to help identify patients most likely to benefit from checkpoint blockade therapies.

In addition, Dr. Flechtner will be participating on the following panel:

  • “For vaccines that are being paired with adjuvant or checkpoint blockade therapies, are we working with the right antigenic targets?”
    Tuesday, April 11 at 5:40 pm ET

About GEN-003
GEN-003 is an investigational T cell-directed immunotherapy designed to elicit both a T cell and B cell (antibody) immune response in patients with genital herpes. In multiple Phase 2 randomized, placebo-controlled clinical trials, GEN-003 has demonstrated the ability to statistically significantly reduce the clinical signs of genital herpes and the rate of viral shedding. The immunotherapy was designed using Genocea’s ATLAS™ platform, which profiled the comprehensive spectrum of actual T cell responses mounted by humans in response to HSV-2 to identify antigen targets that drive protective T cell responses to the virus. If successfully developed and marketed, GEN-003 would be the first new therapy in more than 20 years to treat the large and unsatisfied global genital herpes patient population.


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